NLRP3 inflammasome inhibitor MCC950 can reduce the damage of pancreatic and intestinal barrier function in mice with acute pancreatitis

PURPOSE: Abnormal activation of NOD-like receptor protein 3 (NLRP3) inflammasome can lead to the occurrence and progression of acute pancreatitis. This study investigated the protective effect of MCC950 on pancreatitis mice. METHODS: Eighteen mice were randomly divided into control group, severe acu...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yanghui, Yang, Huobao, Wu, Dansen, Yang, Hangmei, Hong, Donghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633010/
https://www.ncbi.nlm.nih.gov/pubmed/36327405
http://dx.doi.org/10.1590/acb370706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633010/
https://www.ncbi.nlm.nih.gov/pubmed/36327405
http://dx.doi.org/10.1590/acb370706

Ejemplares similares