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Multiplex immunohistochemistry reveals cochlear macrophage heterogeneity and local auditory nerve inflammation in cisplatin-induced hearing loss

Inner ear macrophages play a vital role in cochlear homeostasis. Recent studies have demonstrated the existence of macrophages at different sites of the cochlea, with increased cochlear infiltration as an inflammatory response mechanism to injury. However, current methods, such as conventional immun...

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Detalles Bibliográficos
Autores principales: Bedeir, Mai Mohamed, Ninoyu, Yuzuru, Nakamura, Takashi, Tsujikawa, Takahiro, Hirano, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633043/
https://www.ncbi.nlm.nih.gov/pubmed/36341090
http://dx.doi.org/10.3389/fneur.2022.1015014