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RGS3 and IL1RAPL1 missense variants implicate defective neurotransmission in early-onset inherited schizophrenias

BACKGROUND: Schizophrenia is characterized by hallucinations, delusions and disorganized behaviour. Recessive or X-linked transmissions are rarely described for common psychiatric disorders. We examined the genetics of psychosis to identify rare large-effect variants in patients with extreme schizop...

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Detalles Bibliográficos
Autores principales: Kanwal, Ambreen, Pardo, José V., Naz, Sadaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CMA Impact Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633053/
https://www.ncbi.nlm.nih.gov/pubmed/36318984
http://dx.doi.org/10.1503/jpn.220070