Preclinical evaluation and first in human study of Al(18)F radiolabeled ODAP-urea-based PSMA targeting ligand for PET imaging of prostate cancer

PURPOSE: This study aimed to introduce a novel [(18)F]AlF-labeled ODAP-Urea-based Prostate-specific membrane antigen (PSMA) probe, named [(18)F]AlF-PSMA-137, which was derived from the successful modification of glutamate-like functional group. The preclinically physical and biological characteristi...

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Detalles Bibliográficos
Autores principales: Ren, Ya’nan, Liu, Chen, Liu, Teli, Duan, Xiaojiang, Zhang, Qian, Liu, Jiayue, Wang, Pei, Guo, Qian, Yang, Xing, Du, Peng, Zhu, Hua, Yang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633261/
https://www.ncbi.nlm.nih.gov/pubmed/36338719
http://dx.doi.org/10.3389/fonc.2022.1030187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633261/
https://www.ncbi.nlm.nih.gov/pubmed/36338719
http://dx.doi.org/10.3389/fonc.2022.1030187

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