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Basal extrusion of single‐oncogenic mutant cells induces dome‐like structures with altered microenvironments

At the initial stage of carcinogenesis, oncogenic transformation occurs in single cells within epithelial layers. However, the behavior and fate of the newly emerging transformed cells remain enigmatic. Here, using originally established mouse models, we investigate the fate of RasV12‐transformed ce...

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Detalles Bibliográficos
Autores principales: Shirai, Takanobu, Sekai, Miho, Kozawa, Kei, Sato, Nanami, Tanimura, Nobuyuki, Kon, Shunsuke, Matsumoto, Tomohiro, Murakami, Takeru, Ito, Shoko, Tilston‐Lunel, Andrew, Varelas, Xaralabos, Fujita, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633292/
https://www.ncbi.nlm.nih.gov/pubmed/35816400
http://dx.doi.org/10.1111/cas.15483