Cargando…

CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT

CD155 is a shared ligand for activating and inhibitory immunoreceptors DNAX accessory molecule 1 (DNAM‐1), also called CD226, and T cell immunoglobulin and immunoreceptor tyrosine‐based inhibitory motif domain (TIGIT), which are expressed on natural killer (NK) cells and T cells, and positively and...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuo, Tomohei, Iguchi‐Manaka, Akiko, Shibuya, Akira, Shibuya, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633295/
https://www.ncbi.nlm.nih.gov/pubmed/35947095
http://dx.doi.org/10.1111/cas.15526