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3D matrix promotes cell dedifferentiation into colorectal cancer stem cells via integrin/cytoskeleton/glycolysis signaling

The potential for tumor occurrence triggered by cancer stem cells (CSCs) has emerged as a significant challenge for human colorectal cancer therapy. However, the underlying mechanism of CSC development remains controversial. Our study provided evidence that the bulk of tumor cells could dedifferenti...

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Detalles Bibliográficos
Autores principales: Han, Tong, Jiang, Yuhong, Wang, Xiaobo, Deng, Shuangya, Hu, Yongjun, Jin, Qianqian, Long, Dongju, Liu, Kuijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633319/
https://www.ncbi.nlm.nih.gov/pubmed/36052705
http://dx.doi.org/10.1111/cas.15548