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Human Cyclophilin B Nuclease Activity Revealed via Nucleic Acid‐Based Electrochemical Sensors

Human cyclophilin B (CypB) is oversecreted by pancreatic cancer cells, making it a potential biomarker for early‐stage disease diagnosis. Our group is motivated to develop aptamer‐based assays to measure CypB levels in biofluids. However, human cyclophilins have been postulated to have collateral nu...

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Detalles Bibliográficos
Autores principales: Clark, Vincent, Waters, Kelly, Orsburn, Ben, Bumpus, Namandjé N., Kundu, Nandini, Sczepanski, Jonathan T., Ray, Partha, Arroyo‐Currás, Netzahualcóyotl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633453/
https://www.ncbi.nlm.nih.gov/pubmed/35999181
http://dx.doi.org/10.1002/anie.202211292