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PIK3CA-mutations in breast cancer

PURPOSE: Phosphatidylinositide-3-kinase (PI3K) regulates proliferation and apoptosis; somatic PIK3CA-mutations may activate these processes. Aim of this study was to determine the prevalence of PIK3CA-mutations in a cohort of early stage breast cancer patients and the association to the course of di...

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Detalles Bibliográficos
Autores principales: Reinhardt, Kristin, Stückrath, Kathrin, Hartung, Carolin, Kaufhold, Sandy, Uleer, Christoph, Hanf, Volker, Lantzsch, Tillmann, Peschel, Susanne, John, Jutta, Pöhler, Marleen, Bauer, Marcus, Bürrig, Friedrich Karl, Weigert, Edith, Buchmann, Jörg, Kantelhardt, Eva Johanna, Thomssen, Christoph, Vetter, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633529/
https://www.ncbi.nlm.nih.gov/pubmed/36279023
http://dx.doi.org/10.1007/s10549-022-06637-w