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Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance

Rifamycin antibiotics are a valuable class of antimicrobials for treating infections by mycobacteria and other persistent bacteria owing to their potent bactericidal activity against replicating and non‐replicating pathogens. However, the clinical utility of rifamycins against Mycobacterium abscessu...

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Detalles Bibliográficos
Autores principales: Lan, Tian, Ganapathy, Uday S., Sharma, Sachin, Ahn, Yong‐Mo, Zimmerman, Matthew, Molodtsov, Vadim, Hegde, Pooja, Gengenbacher, Martin, Ebright, Richard H., Dartois, Véronique, Freundlich, Joel S., Dick, Thomas, Aldrich, Courtney C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633546/
https://www.ncbi.nlm.nih.gov/pubmed/36222275
http://dx.doi.org/10.1002/anie.202211498