Prostaglandin-based rAAV-mediated glaucoma gene therapy in Brown Norway rats

Prostaglandin analogs are first-line treatments for open angle glaucoma and while effective at lowering intraocular pressure, they are undermined by patient non-compliance, causing atrophy of the optic nerve and severe visual impairment. Herein, we evaluate the safety and efficacy of a recombinant a...

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Detalles Bibliográficos
Autores principales: Chern, Kristina J., Nettesheim, Emily R., Reid, Christopher A., Li, Nathan W., Marcoe, Gavin J., Lipinski, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633612/
https://www.ncbi.nlm.nih.gov/pubmed/36329259
http://dx.doi.org/10.1038/s42003-022-04134-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633612/
https://www.ncbi.nlm.nih.gov/pubmed/36329259
http://dx.doi.org/10.1038/s42003-022-04134-w

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