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Prostaglandin-based rAAV-mediated glaucoma gene therapy in Brown Norway rats
Prostaglandin analogs are first-line treatments for open angle glaucoma and while effective at lowering intraocular pressure, they are undermined by patient non-compliance, causing atrophy of the optic nerve and severe visual impairment. Herein, we evaluate the safety and efficacy of a recombinant a...
Autores principales: | Chern, Kristina J., Nettesheim, Emily R., Reid, Christopher A., Li, Nathan W., Marcoe, Gavin J., Lipinski, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633612/ https://www.ncbi.nlm.nih.gov/pubmed/36329259 http://dx.doi.org/10.1038/s42003-022-04134-w |
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