RG/RGG repeats in the C. elegans homologs of Nucleolin and GAR1 contribute to sub-nucleolar phase separation

The intrinsically disordered RG/RGG repeat domain is found in several nucleolar and P-granule proteins, but how it influences their phase separation into biomolecular condensates is unclear. We survey all RG/RGG repeats in C. elegans and uncover nucleolar and P-granule-specific RG/RGG motifs. An unc...

Descripción completa

Detalles Bibliográficos
Autores principales: Spaulding, Emily L., Feidler, Alexis M., Cook, Lio A., Updike, Dustin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633708/
https://www.ncbi.nlm.nih.gov/pubmed/36329008
http://dx.doi.org/10.1038/s41467-022-34225-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633708/
https://www.ncbi.nlm.nih.gov/pubmed/36329008
http://dx.doi.org/10.1038/s41467-022-34225-5

Ejemplares similares