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Mapping-friendly sequence reductions: Going beyond homopolymer compression

Sequencing errors continue to pose algorithmic challenges to methods working with sequencing data. One of the simplest and most prevalent techniques for ameliorating the detrimental effects of homopolymer expansion/contraction errors present in long reads is homopolymer compression. It collapses run...

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Detalles Bibliográficos
Autores principales: Blassel, Luc, Medvedev, Paul, Chikhi, Rayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633736/
https://www.ncbi.nlm.nih.gov/pubmed/36339268
http://dx.doi.org/10.1016/j.isci.2022.105305