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Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis

β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications. Apoptosis and autophagy are the main pathways that regulate the balance between cell survival and cell death in response to diverse cell...

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Detalles Bibliográficos
Autores principales: Chaichompoo, Pornthip, Nithipongvanitch, Ramaneeya, Kheansaard, Wasinee, Tubsuwan, Alisa, Srinoun, Kanitta, Vadolas, Jim, Fucharoen, Suthat, Smith, Duncan R., Winichagoon, Pranee, Svasti, Saovaros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633749/
https://www.ncbi.nlm.nih.gov/pubmed/36329049
http://dx.doi.org/10.1038/s41598-022-21249-6