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Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis
β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications. Apoptosis and autophagy are the main pathways that regulate the balance between cell survival and cell death in response to diverse cell...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633749/ https://www.ncbi.nlm.nih.gov/pubmed/36329049 http://dx.doi.org/10.1038/s41598-022-21249-6 |