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Impact of IL-15 and latency reversing agent combinations in the reactivation and NK cell-mediated suppression of the HIV reservoir

Inhibitors of histone deacetylases (HDACis) are major latency reversing agent (LRA) candidates in ‘shock and kill’ strategies to eradicate the HIV reservoir in infected patients. The poor achievements of initial HDACi-based trials and subsequent studies have highlighted the need for more efficient a...

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Detalles Bibliográficos
Autores principales: Covino, Daniela Angela, Desimio, Maria Giovanna, Doria, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633760/
https://www.ncbi.nlm.nih.gov/pubmed/36329160
http://dx.doi.org/10.1038/s41598-022-23010-5