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Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy

Sjögren’s disease (SjD) is a chronic autoimmune sialadenitis resulting in salivary gland hypofunction with dry mouth symptom. Previous studies showed that lysosome-associated membrane protein 3 (LAMP3) overexpression is involved in the development of salivary gland hypofunction associated with SjD....

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Detalles Bibliográficos
Autores principales: Nakamura, Hiroyuki, Tanaka, Tsutomu, Zheng, Changyu, Afione, Sandra A., Warner, Blake M., Noguchi, Masayuki, Atsumi, Tatsuya, Chiorini, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633788/
https://www.ncbi.nlm.nih.gov/pubmed/36329045
http://dx.doi.org/10.1038/s41598-022-21374-2