P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice

Pseudoallergies caused by drugs make disease treatment difficult. Mas-relate G protein-coupled receptor X2 (MRGPRX2), which is specifically expressed in mast cells (MCs), has been implicated in pseudoallergies. High concentrations of therapeutic agents are typically required to stimulate MRGPRX2. Al...

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Detalles Bibliográficos
Autores principales: Yoshida, Kazuki, Tanihara, Shota, Miyashita, Yuki, Obayashi, Kosuke, Ito, Masa-aki, Yamamoto, Kimiko, Imai, Toshiyashu, Matsuoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633816/
https://www.ncbi.nlm.nih.gov/pubmed/36329102
http://dx.doi.org/10.1038/s41598-022-21667-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633816/
https://www.ncbi.nlm.nih.gov/pubmed/36329102
http://dx.doi.org/10.1038/s41598-022-21667-6

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