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PLK2 Single Nucleotide Variant in Gastric Cancer Patients Affects miR-23b-5p Binding

PURPOSE: Chromosomal instability is a hallmark of gastric cancer (GC). It can be driven by single nucleotide variants (SNVs) in cell cycle genes. We investigated the associations between SNVs in candidate genes, PLK2, PLK3, and ATM, and GC risk and clinicopathological features. MATERIALS AND METHODS...

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Detalles Bibliográficos
Autores principales: Dominkuš, Pia Pužar, Mesic, Aner, Hudler, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633926/
https://www.ncbi.nlm.nih.gov/pubmed/36316110
http://dx.doi.org/10.5230/jgc.2022.22.e31