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Sp1-Induced SETDB1 Overexpression Transcriptionally Inhibits HPGD in a β-Catenin-Dependent Manner and Promotes the Proliferation and Metastasis of Gastric Cancer

PURPOSE: Gastric cancer (GC) has high morbidity and mortality, the cure rate of surgical treatment and drug chemotherapy is not ideal. Therefore, development of new treatment strategies is necessary. We aimed to identify the mechanism underlying Sp1 regulation of GC progression. METHODS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Fan, Yaguan, Yang, Libo, Ren, Yi, Wu, Yunhua, Li, Linhai, Li, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633935/
https://www.ncbi.nlm.nih.gov/pubmed/36316108
http://dx.doi.org/10.5230/jgc.2022.22.e26