S-Equol enhances osteoblastic bone formation and prevents bone loss through OPG/RANKL via the PI3K/Akt pathway in streptozotocin-induced diabetic rats

BACKGROUND: This study aimed to explore whether S-Equol delays diabetes-induced osteoporosis and the molecular mechanisms underlying its therapeutic effects. MATERIALS AND METHODS: Thirty-five male Sprague–Dawley rats were randomized into five groups. The diabetic osteoporosis (DOP) group and three...

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Detalles Bibliográficos
Autores principales: Xu, Zhe, Xu, Jing, Li, Shuo, Cui, Hanqiang, Zhang, Guiming, Ni, Xiangmin, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633996/
https://www.ncbi.nlm.nih.gov/pubmed/36337646
http://dx.doi.org/10.3389/fnut.2022.986192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633996/
https://www.ncbi.nlm.nih.gov/pubmed/36337646
http://dx.doi.org/10.3389/fnut.2022.986192

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