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SP1-induced lncRNA MCF2L-AS1 promotes cisplatin resistance in ovarian cancer by regulating IGF2BP1/IGF2/MEK/ERK axis

OBJECTIVE: Cisplatin resistance is a huge problem encountered in ovarian cancer treatment. Our study probed the roles and the underlying mechanisms of lncRNA MCF2L-AS1 in ovarian cancer cisplatin-resistance. METHODS: SKOV3 and IGROV-1 cells were subjected to gradually increasing concentrations of ci...

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Detalles Bibliográficos
Autores principales: Zhu, Yan, Yang, Lijuan, Wang, Jianqing, Li, Yan, Chen, Youguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634094/
https://www.ncbi.nlm.nih.gov/pubmed/36245227
http://dx.doi.org/10.3802/jgo.2022.33.e75