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Targeting fibroblast growth factor (FGF)-inducible 14 (Fn14) for tumor therapy

Fibroblast growth factor-inducible 14 (Fn14) is a member of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) and is activated by its ligand TNF-like weak inducer of apoptosis (TWEAK). The latter occurs as a homotrimeric molecule in a soluble and a membrane-bound form. Soluble TWEAK (sTW...

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Detalles Bibliográficos
Autores principales: Zaitseva, Olena, Hoffmann, Annett, Otto, Christoph, Wajant, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634131/
https://www.ncbi.nlm.nih.gov/pubmed/36339601
http://dx.doi.org/10.3389/fphar.2022.935086