Cargando…
Targeting fibroblast growth factor (FGF)-inducible 14 (Fn14) for tumor therapy
Fibroblast growth factor-inducible 14 (Fn14) is a member of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) and is activated by its ligand TNF-like weak inducer of apoptosis (TWEAK). The latter occurs as a homotrimeric molecule in a soluble and a membrane-bound form. Soluble TWEAK (sTW...
Autores principales: | Zaitseva, Olena, Hoffmann, Annett, Otto, Christoph, Wajant, Harald |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634131/ https://www.ncbi.nlm.nih.gov/pubmed/36339601 http://dx.doi.org/10.3389/fphar.2022.935086 |
Ejemplares similares
-
Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling
por: Siegmund, Daniela, et al.
Publicado: (2023) -
Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism (†)
por: Aido, Ahmed, et al.
Publicado: (2021) -
Basic characterization of antibodies targeting receptors of the tumor necrosis factor receptor superfamily
por: Zaitseva, Olena, et al.
Publicado: (2023) -
The TWEAK Receptor Fn14 is a Novel Therapeutic Target in Melanoma: Immunotoxins Targeting Fn14 Receptor for Malignant Melanoma Treatment
por: Zhou, Hong, et al.
Publicado: (2012) -
Fn14, a Downstream Target of the TGF-β Signaling Pathway, Regulates Fibroblast Activation
por: Chen, Shaoxian, et al.
Publicado: (2015)