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Efficient Anti-Tumor Immunotherapy Using Tumor Epitope-Coated Biodegradable Nanoparticles Combined With Polyinosinic-Polycytidylic Acid and an Anti-PD1 Monoclonal Antibody

Vaccination with tumor peptide epitopes associated with MHC class I molecules is an attractive approach directed at inducing tumor-specific CTLs. However, challenges remain in improving the therapeutic efficacy of peptide epitope vaccines, including the low immunogenicity of peptide epitopes and ins...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Hyun, Park, Ji-Hyun, Lee, Sun-Jae, Lee, Hee-Sung, Jung, Jae-Kyung, Lee, Young-Ran, Cho, Hyun-Il, Kim, Jeong-Ki, Kim, Kyungjae, Park, Chan-Su, Lee, Chong-Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634146/
https://www.ncbi.nlm.nih.gov/pubmed/36381958
http://dx.doi.org/10.4110/in.2022.22.e42