The emerging role of radical chemistry in the amination transformation of highly strained [1.1.1]propellane: Bicyclo[1.1.1]pentylamine as bioisosteres of anilines

Bicyclo[1.1.1]pentylamines (BPCAs), emerging as sp(3)-rich surrogates for aniline and its derivatives, demonstrate unique structural features and physicochemical profiles in medicinal and synthetic chemistry. In recent years, compared with conventional synthetic approaches, the rapid development of...

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Detalles Bibliográficos
Autores principales: Pang, Qiwen, Li, Yang, Xie, Xin, Tang, Jie, Liu, Qian, Peng, Cheng, Li, Xiang, Han, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634170/
https://www.ncbi.nlm.nih.gov/pubmed/36339044
http://dx.doi.org/10.3389/fchem.2022.997944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634170/
https://www.ncbi.nlm.nih.gov/pubmed/36339044
http://dx.doi.org/10.3389/fchem.2022.997944

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