Effects of hypoxia on antigen presentation and T cell-based immune recognition of HPV16-transformed cells

Attempts to develop a therapeutic vaccine against human papillomavirus (HPV)-induced malignancies have mostly not been clinically successful to date. One reason may be the hypoxic microenvironment present in most tumors, including cervical cancer. Hypoxia dysregulates the levels of human leukocyte a...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohan, Nitya, Wellach, Kathrin, Özerdem, Ceren, Veits, Nisha, Förster, Jonas D., Foehr, Sophia, Bonsack, Maria, Riemer, Angelika B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634485/
https://www.ncbi.nlm.nih.gov/pubmed/36341354
http://dx.doi.org/10.3389/fimmu.2022.918528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634485/
https://www.ncbi.nlm.nih.gov/pubmed/36341354
http://dx.doi.org/10.3389/fimmu.2022.918528

Ejemplares similares