Cargando…

Effects of hypoxia on antigen presentation and T cell-based immune recognition of HPV16-transformed cells

Attempts to develop a therapeutic vaccine against human papillomavirus (HPV)-induced malignancies have mostly not been clinically successful to date. One reason may be the hypoxic microenvironment present in most tumors, including cervical cancer. Hypoxia dysregulates the levels of human leukocyte a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohan, Nitya, Wellach, Kathrin, Özerdem, Ceren, Veits, Nisha, Förster, Jonas D., Foehr, Sophia, Bonsack, Maria, Riemer, Angelika B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634485/ https://www.ncbi.nlm.nih.gov/pubmed/36341354 http://dx.doi.org/10.3389/fimmu.2022.918528

Ejemplares similares

Characterization of DoTc2 4510—Identifying HPV16 Presence in a Cervical Carcinoma Cell Line Previously Considered to Be HPV-Negative
por: Vučković, Nika, et al.
Publicado: (2023)

Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice
por: Schifflers, Christoph, et al.
Publicado: (2023)

A Targeted LC‐MS Strategy for Low‐Abundant HLA Class‐I‐Presented Peptide Detection Identifies Novel Human Papillomavirus T‐Cell Epitopes
por: Blatnik, Renata, et al.
Publicado: (2018)

Generation of affibody molecules specific for HPV16 E7 recognition
por: Xue, Xiangyang, et al.
Publicado: (2016)

Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with HPV16 E7 oncoprotein
por: Rodolico, Vito, et al.
Publicado: (2011)

Inducing Immunity Where It Matters: Orthotopic HPV Tumor Models and Therapeutic Vaccinations
por: Zottnick, Samantha, et al.
Publicado: (2020)

Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer
por: Anderson, K S, et al.
Publicado: (2011)

Evolution and Taxonomic Classification of Human Papillomavirus 16 (HPV16)-Related Variant Genomes: HPV31, HPV33, HPV35, HPV52, HPV58 and HPV67
por: Chen, Zigui, et al.
Publicado: (2011)

Emotion recognition based on EEG features in movie clips with channel selection
por: Özerdem, Mehmet Siraç, et al.
Publicado: (2017)

Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors
por: Jimeno, Antonio, et al.
Publicado: (2023)

Definition and Characterization of SOX11-Derived T Cell Epitopes towards Immunotherapy of Glioma
por: Liu, Yibin, et al.
Publicado: (2023)

The Invisible Enemy – How Human Papillomaviruses Avoid Recognition and Clearance by the Host Immune System
por: Grabowska, Agnieszka K, et al.
Publicado: (2012)

Light contamination in stable isotope-labelled internal peptide standards is frequent and a potential source of false discovery and quantitation error in proteomics
por: Salek, Mogjiborahman, et al.
Publicado: (2022)

HPV16 Entry into Epithelial Cells: Running a Gauntlet
por: Mikuličić, Snježana, et al.
Publicado: (2021)

Anti-HPV16 Antibody Titers Prior to an Incident Cervical HPV16/31 Infection
por: Gradissimo, Ana, et al.
Publicado: (2021)

HPV16 infection decreases vaccine-induced HPV16 antibody avidity: the CVT trial
por: Tsang, Sabrina H., et al.
Publicado: (2022)

Prevalence of HPV 16 and HPV 18 Lineages in Galicia, Spain
por: Pérez, Sonia, et al.
Publicado: (2014)

Interaction of HPV16 and Cutaneous HPV in Head and Neck Cancer
por: Al-Soneidar, Walid A., et al.
Publicado: (2022)

HPV-16 Expression and Loss of Cell Differentiation in Primary Bladder Tumors
por: Pang, Lei, et al.
Publicado: (2022)

Flavonol and imidazole derivatives block HPV16 E6 activities and reactivate apoptotic pathways in HPV(+) cells
por: Yuan, C-H, et al.
Publicado: (2016)

Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positive Human Cervical Cancer Cells
por: Hu, Zheng, et al.
Publicado: (2014)

Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer Cells
por: Zhang, Chunlin, et al.
Publicado: (2015)

HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial
por: van Poelgeest, Mariette I E, et al.
Publicado: (2013)

Antibodies against human papillomavirus type 16 (HPV-16) and conjunctival squamous cell neoplasia in Uganda
por: Waddell, K, et al.
Publicado: (2003)

p16 in HPV-associated cancers
por: Munger, Karl, et al.
Publicado: (2013)

Detection of HPV16 in Esophageal Cancer in a High-Incidence Region of Malawi
por: Geßner, Anja Lidwina, et al.
Publicado: (2018)

Dynamic response of HPV16/anti-HPV16 pairs with unbinding events studied by atomic force microscopy
por: Lin, Shiming, et al.
Publicado: (2016)

Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway
por: Ding, Wencheng, et al.
Publicado: (2018)

Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation
por: Hee Lee, Sung, et al.
Publicado: (2015)

Triage of HPV-positive women in Norway using cytology, HPV16/18 genotyping and HPV persistence
por: Arbyn, Marc, et al.
Publicado: (2020)

Reference MicroRNAs for RT-qPCR Assays in Cervical Cancer Patients and Their Application to Studies of HPV16 and Hypoxia Biomarkers()()
por: Nilsen, Anja, et al.
Publicado: (2019)

Human Papillomavirus 16 (HPV16) E2 Repression of TWIST1 Transcription Is a Potential Mediator of HPV16 Cancer Outcomes
por: Fontan, Christian T., et al.
Publicado: (2020)

An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
por: Carper, Miranda B., et al.
Publicado: (2019)

Is It Time to Genotype Beyond HPV16 and HPV18 for Cervical Cancer Screening?
por: Chua, Brandon Wen Bing, et al.
Publicado: (2022)

HPV16 and HPV18 Genome Structure, Expression, and Post-Transcriptional Regulation
por: Yu, Lulu, et al.
Publicado: (2022)

HPV16 Seropositivity and Subsequent HPV16 Infection Risk in a Naturally Infected Population: Comparison of Serological Assays
por: Lin, Shih-Wen, et al.
Publicado: (2013)

A novel HPV16 E7-affitoxin for targeted therapy of HPV16-induced human cervical cancer
por: Jiang, Pengfei, et al.
Publicado: (2018)

HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection
por: Beachler, Daniel C., et al.
Publicado: (2016)

Assessment of HPV 16, HPV 18, p16 expression in advanced stage laryngeal cancer patients and prognostic significance()()
por: Dogantemur, Selman, et al.
Publicado: (2019)

Hypoxia and Its Influence on Radiotherapy Response of HPV-Positive and HPV-Negative Head and Neck Cancer
por: Wegge, Marilyn, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1kenojju32snmtv6pvvpkacv9e