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Targeting DNA damage response as a potential therapeutic strategy for head and neck squamous cell carcinoma

Cells experience both endogenous and exogenous DNA damage daily. To maintain genome integrity and suppress tumorigenesis, individuals have evolutionarily acquired a series of repair functions, termed DNA damage response (DDR), to repair DNA damage and ensure the accurate transmission of genetic info...

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Detalles Bibliográficos
Autores principales: Lei, Huimin, He, Ading, Jiang, Yingying, Ruan, Min, Han, Nannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634729/
https://www.ncbi.nlm.nih.gov/pubmed/36338767
http://dx.doi.org/10.3389/fonc.2022.1031944