O-GlcNAcylation Coordinates Glutaminolysis by Regulating the Stability and Membrane Trafficking of ASCT2 in Hepatic Stellate Cells

BACKGROUND AND AIMS: Recognition of excessive activation of hepatic stellate cells (HSCs) in liver fibrosis prompted us to investigate the regulatory mechanisms of HSCs. We aimed to examine the role of O-GlcNAcylation modification of alanine, serine, cysteine transporter 2 (ASCT2) in HSCs and liver...

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Detalles Bibliográficos
Autores principales: Wang, Feixia, Chen, Li, Zhang, Biyun, Li, Zhanghao, Shen, Min, Tang, Li, Zhang, Zili, Shao, Jiangjuan, Zhang, Feng, Zheng, Shizhong, Tan, Shanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634767/
https://www.ncbi.nlm.nih.gov/pubmed/36381090
http://dx.doi.org/10.14218/JCTH.2021.00413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634767/
https://www.ncbi.nlm.nih.gov/pubmed/36381090
http://dx.doi.org/10.14218/JCTH.2021.00413

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