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Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose

[Image: see text] The opioid crisis continues to claim many lives, with a particular issue being the ready availability and use (whether intentional or accidental) of fentanyl and fentanyl analogues. Fentanyl is both potent and longer-acting than naloxone, the standard of care for overdose reversal,...

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Detalles Bibliográficos
Autores principales: Disney, Alex, Olson, Keith M., Shafer, Amanda M., Moore, Sierra C., Anand, Jessica P., Traynor, John R., Husbands, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634796/
https://www.ncbi.nlm.nih.gov/pubmed/36223082
http://dx.doi.org/10.1021/acschemneuro.2c00464