Orthogonal Enzyme-Driven Timers for DNA Strand Displacement Reactions

[Image: see text] Here, we demonstrate a strategy to rationally program a delayed onset of toehold-mediated DNA strand displacement reactions (SDRs). The approach is based on blocker strands that efficiently inhibit the strand displacement by binding to the toehold domain of the target DNA. Specific...

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Detalles Bibliográficos
Autores principales: Bucci, Juliette, Irmisch, Patrick, Del Grosso, Erica, Seidel, Ralf, Ricci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634797/
https://www.ncbi.nlm.nih.gov/pubmed/36257052
http://dx.doi.org/10.1021/jacs.2c06599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634797/
https://www.ncbi.nlm.nih.gov/pubmed/36257052
http://dx.doi.org/10.1021/jacs.2c06599

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