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Orthogonal Enzyme-Driven Timers for DNA Strand Displacement Reactions
[Image: see text] Here, we demonstrate a strategy to rationally program a delayed onset of toehold-mediated DNA strand displacement reactions (SDRs). The approach is based on blocker strands that efficiently inhibit the strand displacement by binding to the toehold domain of the target DNA. Specific...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634797/ https://www.ncbi.nlm.nih.gov/pubmed/36257052 http://dx.doi.org/10.1021/jacs.2c06599 |