Mechanochemistry Facilitates a Single-Crystal X-ray Structure Determination of Free Base Naloxone Anhydrate

[Image: see text] A method to obtain single crystals of the opioid antagonist naloxone in the free base form is facilitated using mechanochemistry. The application of mechanochemistry reduces the number of steps and makes single crystals readily available from solution compared to using an approach...

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Detalles Bibliográficos
Autores principales: Ortiz-de León, Celymar, Hartwick, Christopher J., Stuedemann, Clara A., Brogden, Nicole K., MacGillivray, Leonard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634803/
https://www.ncbi.nlm.nih.gov/pubmed/36345388
http://dx.doi.org/10.1021/acs.cgd.2c00831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634803/
https://www.ncbi.nlm.nih.gov/pubmed/36345388
http://dx.doi.org/10.1021/acs.cgd.2c00831

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