Cargando…
Variation in ubiquitin system genes creates substrate-specific effects on proteasomal protein degradation
Precise control of protein degradation is critical for life, yet how natural genetic variation affects this essential process is largely unknown. Here, we developed a statistically powerful mapping approach to characterize how genetic variation affects protein degradation by the ubiquitin-proteasome...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634822/ https://www.ncbi.nlm.nih.gov/pubmed/36218234 http://dx.doi.org/10.7554/eLife.79570 |