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Ribose Alters the Photochemical Properties of the Nucleobase in Thionated Nucleosides

[Image: see text] Substitution of exocyclic oxygen with sulfur was shown to substantially influence the properties of RNA/DNA bases, which are crucial for prebiotic chemistry and photodynamic therapies. Upon UV irradiation, thionucleobases were shown to efficiently populate triplet excited states an...

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Detalles Bibliográficos
Autores principales: Janicki, Mikołaj J., Kufner, Corinna L., Todd, Zoe R., Kim, Seohyun C., O’Flaherty, Derek K., Szostak, Jack W., Šponer, Jiří, Góra, Robert W., Sasselov, Dimitar D., Szabla, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634911/
https://www.ncbi.nlm.nih.gov/pubmed/34260253
http://dx.doi.org/10.1021/acs.jpclett.1c01384