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MARVEL domain containing CMTM4 affects CXCR4 trafficking

The MARVEL proteins CMTM4 and CMTM6 control PD-L1, thereby influencing tumor immunity. We found that defective zebrafish cmtm4 slowed the development of the posterior lateral line (pLL) by altering the Cxcr4b gradient across the pLL primordium (pLLP). Analysis in mammalian cells uncovered that CMTM4...

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Detalles Bibliográficos
Autores principales: Bona, Alexandra, Seifert, Michael, Thünauer, Roland, Zodel, Kyra, Frew, Ian J., Römer, Winfried, Walz, Gerd, Yakulov, Toma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634968/
https://www.ncbi.nlm.nih.gov/pubmed/36044337
http://dx.doi.org/10.1091/mbc.E22-05-0152