Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells

Keratin intermediate filaments convey mechanical stability and protection against stress to epithelial cells. Keratins are essential for colon health, as seen in keratin 8 knockout (K8(−/−)) mice exhibiting a colitis phenotype. We hypothesized that keratins support the nuclear envelope and lamina in...

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Detalles Bibliográficos
Autores principales: Stenvall, Carl-Gustaf A., Nyström, Joel H., Butler-Hallissey, Ciarán, Jansson, Theresia, Heikkilä, Taina R. H., Adam, Stephen A., Foisner, Roland, Goldman, Robert D., Ridge, Karen M., Toivola, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634972/
https://www.ncbi.nlm.nih.gov/pubmed/36001365
http://dx.doi.org/10.1091/mbc.E20-06-0387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634972/
https://www.ncbi.nlm.nih.gov/pubmed/36001365
http://dx.doi.org/10.1091/mbc.E20-06-0387

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