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Tau differentially regulates the transport of early endosomes and lysosomes

Microtubule-associated proteins (MAPs) modulate the motility of kinesin and dynein along microtubules to control the transport of vesicles and organelles. The neuronal MAP tau inhibits kinesin-dependent transport. Phosphorylation of tau at Tyr-18 by fyn kinase results in weakened inhibition of kines...

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Detalles Bibliográficos
Autores principales: Balabanian, Linda, Lessard, Dominique V., Swaminathan, Karthikeyan, Yaninska, Pamela, Sébastien, Muriel, Wang, Samuel, Stevens, Piper W., Wiseman, Paul W., Berger, Christopher L., Hendricks, Adam G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634973/
https://www.ncbi.nlm.nih.gov/pubmed/36129768
http://dx.doi.org/10.1091/mbc.E22-01-0018