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Tau differentially regulates the transport of early endosomes and lysosomes
Microtubule-associated proteins (MAPs) modulate the motility of kinesin and dynein along microtubules to control the transport of vesicles and organelles. The neuronal MAP tau inhibits kinesin-dependent transport. Phosphorylation of tau at Tyr-18 by fyn kinase results in weakened inhibition of kines...
Autores principales: | Balabanian, Linda, Lessard, Dominique V., Swaminathan, Karthikeyan, Yaninska, Pamela, Sébastien, Muriel, Wang, Samuel, Stevens, Piper W., Wiseman, Paul W., Berger, Christopher L., Hendricks, Adam G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634973/ https://www.ncbi.nlm.nih.gov/pubmed/36129768 http://dx.doi.org/10.1091/mbc.E22-01-0018 |
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