Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells

DNA replication is normally coupled with centriole duplication in the cell cycle. Trophoblast giant cells (TGCs) of the placenta undergo endocycles resulting in polyploidy but their centriole state is not known. We used a cell culture model for TGC differentiation to examine centriole and centrosome...

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Detalles Bibliográficos
Autores principales: Buss, Garrison, Stratton, Miranda B., Milenkovic, Ljiljana, Stearns, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634975/
https://www.ncbi.nlm.nih.gov/pubmed/36001376
http://dx.doi.org/10.1091/mbc.E22-05-0182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634975/
https://www.ncbi.nlm.nih.gov/pubmed/36001376
http://dx.doi.org/10.1091/mbc.E22-05-0182

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