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Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells
DNA replication is normally coupled with centriole duplication in the cell cycle. Trophoblast giant cells (TGCs) of the placenta undergo endocycles resulting in polyploidy but their centriole state is not known. We used a cell culture model for TGC differentiation to examine centriole and centrosome...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634975/ https://www.ncbi.nlm.nih.gov/pubmed/36001376 http://dx.doi.org/10.1091/mbc.E22-05-0182 |