Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents

BACKGROUND: A series of coumarin-indole hybrids was synthesized as the new α-glucosidase inhibitors. The title hybrids were considered as α-glucosidase inhibitors because had two active pharmacophores against α-glucosidase: coumarin and indole. METHODS: The thirteen various derivatives 4a–m were syn...

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Detalles Bibliográficos
Autores principales: Niri, Davood Rezapour, Sayahi, Mohammad Hosein, Behrouz, Somayeh, Moazzam, Ali, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Larijani, Bagher, Rastegar, Hossein, Mohammadi-Khanaposhtani, Maryam, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635080/
https://www.ncbi.nlm.nih.gov/pubmed/36329490
http://dx.doi.org/10.1186/s13065-022-00882-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635080/
https://www.ncbi.nlm.nih.gov/pubmed/36329490
http://dx.doi.org/10.1186/s13065-022-00882-2

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