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A photodynamically sensitized dendritic cell vaccine that promotes the anti-tumor effects of anti-PD-L1 monoclonal antibody in a murine model of head and neck squamous cell carcinoma

BACKGROUND: Immune checkpoint inhibitors are promising tools in combating several cancers, including head and neck squamous cell carcinoma (HNSCC). However, a substantial portion of HNSCC patients do not respond to PD-L1 antibody. Here we describe a photodynamic therapeutic (PDT) approach to enhance...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Wang, Ding, Cheng, Jinzhang, Sun, Jicheng, Kalvakolanu, Dhan V., Zhao, Xue, Wang, Di, You, Yunhan, Zhang, Ling, Yu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635135/
https://www.ncbi.nlm.nih.gov/pubmed/36329529
http://dx.doi.org/10.1186/s12967-022-03707-x