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HIF-1α and Caspase-3 expression in aggressive papillary thyroid carcinoma

BACKGROUND: Tumor cells adapt to hypoxia by regulating transcription factors that involved in regulation of metabolism, angiogenesis, cell proliferation, and apoptosis. Under hypoxic conditions, hypoxia-inducible factor-1 (HIF-1), consisting of HIF-1α and HIF-1β subunits, acts as a key transcription...

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Detalles Bibliográficos
Autores principales: Zhang, Lili, Shi, Baixue, Hu, Mingyang, Qian, Linxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635136/
https://www.ncbi.nlm.nih.gov/pubmed/36329448
http://dx.doi.org/10.1186/s12957-022-02815-8