Single cell profiling of CD45(+) spinal cord cells reveals microglial and B cell heterogeneity and crosstalk following spinal cord injury

BACKGROUND: Immune cells play crucial roles after spinal cord injury (SCI). However, incomplete knowledge of immune contributions to injury and repair hinders development of SCI therapies. We leveraged single-cell observations to describe key populations of immune cells present in the spinal cord an...

Descripción completa

Detalles Bibliográficos
Autores principales: Fisher, Elizabeth S., Amarante, Matthew A., Lowry, Natasha, Lotz, Steven, Farjood, Farhad, Temple, Sally, Hill, Caitlin E., Kiehl, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635187/
https://www.ncbi.nlm.nih.gov/pubmed/36333772
http://dx.doi.org/10.1186/s12974-022-02627-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635187/
https://www.ncbi.nlm.nih.gov/pubmed/36333772
http://dx.doi.org/10.1186/s12974-022-02627-3

Ejemplares similares