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Plectin linkages are mechanosensitive and required for the nuclear piston mechanism of three-dimensional cell migration

Cells migrating through physiologically relevant three-dimensional (3D) substrates such as cell-derived matrix (CDM) use actomyosin and vimentin intermediate filaments to pull the nucleus forward and pressurize the front of the cell as part of the nuclear piston mechanism of 3D migration. In this st...

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Detalles Bibliográficos
Autores principales: Marks, Pragati C., Hewitt, Breanne R., Baird, Michelle A., Wiche, Gerhard, Petrie, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635290/
https://www.ncbi.nlm.nih.gov/pubmed/35857713
http://dx.doi.org/10.1091/mbc.E21-08-0414