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The adaptor protein chaperone AAGAB stabilizes AP-4 complex subunits

Adaptor protein 4 (AP-4) is a heterotetrameric complex composed of ε, β4, μ4, and σ4 subunits that mediates export of a subset of transmembrane cargos, including autophagy protein 9A (ATG9A), from the trans-Golgi network (TGN). AP-4 has received particular attention in recent years because mutations...

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Detalles Bibliográficos
Autores principales: Mattera, Rafael, De Pace, Raffaella, Bonifacino, Juan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635299/
https://www.ncbi.nlm.nih.gov/pubmed/35976721
http://dx.doi.org/10.1091/mbc.E22-05-0177