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The mitochondrial RNA granule modulates manganese-dependent cell toxicity

Prolonged manganese exposure causes manganism, a neurodegenerative movement disorder. The identity of adaptive and nonadaptive cellular processes targeted by manganese remains mostly unexplored. Here we study mechanisms engaged by manganese in genetic cellular models known to increase susceptibility...

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Detalles Bibliográficos
Autores principales: Werner, E., Gokhale, A., Ackert, M., Xu, C., Wen, Z., Roberts, A. M., Roberts, B. R., Vrailas-Mortimer, A., Crocker, A., Faundez, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635304/
https://www.ncbi.nlm.nih.gov/pubmed/35921164
http://dx.doi.org/10.1091/mbc.E22-03-0096