PIN1 protects auditory hair cells from senescence via autophagy

BACKGROUND: Age-related hearing loss is an increasing sensorineural hearing loss. But the pathogenesis of ARHL has not been clarified. Herein, we studied the role and significance of PIN1 in regulating autophagy activity in senescence HEI-OC1cells and HCs. METHODS AND RESULTS: C57BL/6 mice and HEI-O...

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Detalles Bibliográficos
Autores principales: Lv, Zhe, Zhang, Yanzhuo, Cao, Huan, Liu, Qingjuan, Feng, Xiaojuan, Yin, Huan, Wang, BaoShan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635358/
https://www.ncbi.nlm.nih.gov/pubmed/36340199
http://dx.doi.org/10.7717/peerj.14267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635358/
https://www.ncbi.nlm.nih.gov/pubmed/36340199
http://dx.doi.org/10.7717/peerj.14267

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